Detection of SARS-COV-2 by functionally imprinted micelles

The near real-time detection of airborne particles-of-interest is needed for avoiding current/future threats. The incorporation of imprinted particles into a micelle-based electrochemical cell produced a signal when brought into contact with particle analytes (such as SARS-COV-2), previously imprint...

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Detalles Bibliográficos
Autores principales: Hubbard, Lance R., Allen, Caleb J., Sims, Amy C., Engbrecht, Kristin M., O’Hara, Matthew J., Johnson, Jared C., Morrison, Samuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592882/
https://www.ncbi.nlm.nih.gov/pubmed/36311275
http://dx.doi.org/10.1557/s43579-022-00242-0
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author Hubbard, Lance R.
Allen, Caleb J.
Sims, Amy C.
Engbrecht, Kristin M.
O’Hara, Matthew J.
Johnson, Jared C.
Morrison, Samuel S.
author_facet Hubbard, Lance R.
Allen, Caleb J.
Sims, Amy C.
Engbrecht, Kristin M.
O’Hara, Matthew J.
Johnson, Jared C.
Morrison, Samuel S.
author_sort Hubbard, Lance R.
collection PubMed
description The near real-time detection of airborne particles-of-interest is needed for avoiding current/future threats. The incorporation of imprinted particles into a micelle-based electrochemical cell produced a signal when brought into contact with particle analytes (such as SARS-COV-2), previously imprinted onto the structure. Nanoamp scales of signals were generated from what may’ve been individual virus-micelle interactions. The system showed selectivity when tested against similar size and morphology particles. The technology was compatible with airborne aerosol sampling techniques. Overall, the application of imprinted micelle technology could provide near real-time detection methods to a host of possible analytes of interest in the field. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1557/s43579-022-00242-0.
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spelling pubmed-95928822022-10-25 Detection of SARS-COV-2 by functionally imprinted micelles Hubbard, Lance R. Allen, Caleb J. Sims, Amy C. Engbrecht, Kristin M. O’Hara, Matthew J. Johnson, Jared C. Morrison, Samuel S. MRS Commun Research Letter The near real-time detection of airborne particles-of-interest is needed for avoiding current/future threats. The incorporation of imprinted particles into a micelle-based electrochemical cell produced a signal when brought into contact with particle analytes (such as SARS-COV-2), previously imprinted onto the structure. Nanoamp scales of signals were generated from what may’ve been individual virus-micelle interactions. The system showed selectivity when tested against similar size and morphology particles. The technology was compatible with airborne aerosol sampling techniques. Overall, the application of imprinted micelle technology could provide near real-time detection methods to a host of possible analytes of interest in the field. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1557/s43579-022-00242-0. Springer International Publishing 2022-10-25 2022 /pmc/articles/PMC9592882/ /pubmed/36311275 http://dx.doi.org/10.1557/s43579-022-00242-0 Text en © Battelle Memorial Institute, under exclusive license to The Materials Research Society 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Research Letter
Hubbard, Lance R.
Allen, Caleb J.
Sims, Amy C.
Engbrecht, Kristin M.
O’Hara, Matthew J.
Johnson, Jared C.
Morrison, Samuel S.
Detection of SARS-COV-2 by functionally imprinted micelles
title Detection of SARS-COV-2 by functionally imprinted micelles
title_full Detection of SARS-COV-2 by functionally imprinted micelles
title_fullStr Detection of SARS-COV-2 by functionally imprinted micelles
title_full_unstemmed Detection of SARS-COV-2 by functionally imprinted micelles
title_short Detection of SARS-COV-2 by functionally imprinted micelles
title_sort detection of sars-cov-2 by functionally imprinted micelles
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592882/
https://www.ncbi.nlm.nih.gov/pubmed/36311275
http://dx.doi.org/10.1557/s43579-022-00242-0
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