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Traditional Chinese medicine promotes the control and treatment of dementia

Dementia is a syndrome that impairs learning and memory. To date, there is no effective therapy for dementia. Current prescription drugs, such as cholinesterase inhibitors, fail to improve the condition of dementia and are often accompanied by severe adverse effects. In recent years, the number of s...

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Autores principales: Tao, Pengyu, Xu, Wenxin, Gu, Simeng, Shi, Haiyan, Wang, Qian, Xu, Yuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592982/
https://www.ncbi.nlm.nih.gov/pubmed/36304171
http://dx.doi.org/10.3389/fphar.2022.1015966
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author Tao, Pengyu
Xu, Wenxin
Gu, Simeng
Shi, Haiyan
Wang, Qian
Xu, Yuzhen
author_facet Tao, Pengyu
Xu, Wenxin
Gu, Simeng
Shi, Haiyan
Wang, Qian
Xu, Yuzhen
author_sort Tao, Pengyu
collection PubMed
description Dementia is a syndrome that impairs learning and memory. To date, there is no effective therapy for dementia. Current prescription drugs, such as cholinesterase inhibitors, fail to improve the condition of dementia and are often accompanied by severe adverse effects. In recent years, the number of studies into the use of traditional Chinese medicine (TCM) for dementia treatment has increased, revealing a formula that could significantly improve memory and cognitive dysfunctions in animal models. TCM showed fewer adverse effects, lower costs, and improved suitability for long-term use compared with currently prescribed drugs. Due to the complexity of ingredients and variations in bioactivity of herbal medicines, the multi-target nature of the traditional Chinese formula affected the outcome of dementia therapy. Innovations in TCM will create a platform for the development of new drugs for the prevention and treatment of dementia, further strengthening and enhancing the current influence of TCM.
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spelling pubmed-95929822022-10-26 Traditional Chinese medicine promotes the control and treatment of dementia Tao, Pengyu Xu, Wenxin Gu, Simeng Shi, Haiyan Wang, Qian Xu, Yuzhen Front Pharmacol Pharmacology Dementia is a syndrome that impairs learning and memory. To date, there is no effective therapy for dementia. Current prescription drugs, such as cholinesterase inhibitors, fail to improve the condition of dementia and are often accompanied by severe adverse effects. In recent years, the number of studies into the use of traditional Chinese medicine (TCM) for dementia treatment has increased, revealing a formula that could significantly improve memory and cognitive dysfunctions in animal models. TCM showed fewer adverse effects, lower costs, and improved suitability for long-term use compared with currently prescribed drugs. Due to the complexity of ingredients and variations in bioactivity of herbal medicines, the multi-target nature of the traditional Chinese formula affected the outcome of dementia therapy. Innovations in TCM will create a platform for the development of new drugs for the prevention and treatment of dementia, further strengthening and enhancing the current influence of TCM. Frontiers Media S.A. 2022-10-11 /pmc/articles/PMC9592982/ /pubmed/36304171 http://dx.doi.org/10.3389/fphar.2022.1015966 Text en Copyright © 2022 Tao, Xu, Gu, Shi, Wang and Xu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Tao, Pengyu
Xu, Wenxin
Gu, Simeng
Shi, Haiyan
Wang, Qian
Xu, Yuzhen
Traditional Chinese medicine promotes the control and treatment of dementia
title Traditional Chinese medicine promotes the control and treatment of dementia
title_full Traditional Chinese medicine promotes the control and treatment of dementia
title_fullStr Traditional Chinese medicine promotes the control and treatment of dementia
title_full_unstemmed Traditional Chinese medicine promotes the control and treatment of dementia
title_short Traditional Chinese medicine promotes the control and treatment of dementia
title_sort traditional chinese medicine promotes the control and treatment of dementia
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592982/
https://www.ncbi.nlm.nih.gov/pubmed/36304171
http://dx.doi.org/10.3389/fphar.2022.1015966
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