Determination of (-)-epigallocatechin-3-gallate octaacetate and its metabolites in plasma of rats for pharmacokinetic study by ultra-performance-liquid-chromatography coupled to quadrupole-time-of-flight-mass-spectrometry

(-)-Epigallocatechin-gallate octaacetate (pro-EGCG), a prodrug of epigallocatechin-gallate (EGCG), has been used for pre-clinical study for the treatment of endometriosis. A validated analytical method has been developed for the determination of plasma pro-EGCG and its metabolites after oral adminis...

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Detalles Bibliográficos
Autores principales: Chu, Kai On, Man, Gene Chi Wai, Hung, Sze Wan, Chan, Tak Hang, Lee, Wai Yip Thomas, Chan, Kwok Ping, Pang, Chi Pui, Wang, Chi Chiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592989/
https://www.ncbi.nlm.nih.gov/pubmed/36304154
http://dx.doi.org/10.3389/fphar.2022.1025053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592989/
https://www.ncbi.nlm.nih.gov/pubmed/36304154
http://dx.doi.org/10.3389/fphar.2022.1025053

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