Liver Biopsy-confirmed Primary Hepatic Amyloidosis with Only Jaundice As the Initial Symptom: An Autopsy Case Report

Amyloidosis causes various symptoms in many organs of the body, but amyloidosis that presents with liver damage alone has never been reported. We treated an 83-year-old man with amyloidosis who presented with liver damage alone. The liver damage in this patient was histologically proven to be liver...

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Autores principales: Ueno, Hirotsugu, Douhara, Akitoshi, Osaki, Yui, Koizumi, Aritoshi, Yorioka, Nobuyuki, Ueda, Shigehiko, Tsutsumi, Masahiro, Yoshiji, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593147/
https://www.ncbi.nlm.nih.gov/pubmed/35228432
http://dx.doi.org/10.2169/internalmedicine.9189-21
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author Ueno, Hirotsugu
Douhara, Akitoshi
Osaki, Yui
Koizumi, Aritoshi
Yorioka, Nobuyuki
Ueda, Shigehiko
Tsutsumi, Masahiro
Yoshiji, Hitoshi
author_facet Ueno, Hirotsugu
Douhara, Akitoshi
Osaki, Yui
Koizumi, Aritoshi
Yorioka, Nobuyuki
Ueda, Shigehiko
Tsutsumi, Masahiro
Yoshiji, Hitoshi
author_sort Ueno, Hirotsugu
collection PubMed
description Amyloidosis causes various symptoms in many organs of the body, but amyloidosis that presents with liver damage alone has never been reported. We treated an 83-year-old man with amyloidosis who presented with liver damage alone. The liver damage in this patient was histologically proven to be liver amyloidosis. The administration of bortezomib and dexamethasone was not effective, so he rapidly died of liver failure. An aggressive liver biopsy should be considered when unexplained jaundice is observed.
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spelling pubmed-95931472022-11-07 Liver Biopsy-confirmed Primary Hepatic Amyloidosis with Only Jaundice As the Initial Symptom: An Autopsy Case Report Ueno, Hirotsugu Douhara, Akitoshi Osaki, Yui Koizumi, Aritoshi Yorioka, Nobuyuki Ueda, Shigehiko Tsutsumi, Masahiro Yoshiji, Hitoshi Intern Med Case Report Amyloidosis causes various symptoms in many organs of the body, but amyloidosis that presents with liver damage alone has never been reported. We treated an 83-year-old man with amyloidosis who presented with liver damage alone. The liver damage in this patient was histologically proven to be liver amyloidosis. The administration of bortezomib and dexamethasone was not effective, so he rapidly died of liver failure. An aggressive liver biopsy should be considered when unexplained jaundice is observed. The Japanese Society of Internal Medicine 2022-02-26 2022-10-01 /pmc/articles/PMC9593147/ /pubmed/35228432 http://dx.doi.org/10.2169/internalmedicine.9189-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ueno, Hirotsugu
Douhara, Akitoshi
Osaki, Yui
Koizumi, Aritoshi
Yorioka, Nobuyuki
Ueda, Shigehiko
Tsutsumi, Masahiro
Yoshiji, Hitoshi
Liver Biopsy-confirmed Primary Hepatic Amyloidosis with Only Jaundice As the Initial Symptom: An Autopsy Case Report
title Liver Biopsy-confirmed Primary Hepatic Amyloidosis with Only Jaundice As the Initial Symptom: An Autopsy Case Report
title_full Liver Biopsy-confirmed Primary Hepatic Amyloidosis with Only Jaundice As the Initial Symptom: An Autopsy Case Report
title_fullStr Liver Biopsy-confirmed Primary Hepatic Amyloidosis with Only Jaundice As the Initial Symptom: An Autopsy Case Report
title_full_unstemmed Liver Biopsy-confirmed Primary Hepatic Amyloidosis with Only Jaundice As the Initial Symptom: An Autopsy Case Report
title_short Liver Biopsy-confirmed Primary Hepatic Amyloidosis with Only Jaundice As the Initial Symptom: An Autopsy Case Report
title_sort liver biopsy-confirmed primary hepatic amyloidosis with only jaundice as the initial symptom: an autopsy case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593147/
https://www.ncbi.nlm.nih.gov/pubmed/35228432
http://dx.doi.org/10.2169/internalmedicine.9189-21
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