Methicillin-resistant Staphylococcus aureus Necrotizing Bronchitis after Radiotherapy in Combination with Axitinib

A 38-year-old man with renal cell carcinoma was referred to our hospital because of a productive cough. He had received radiotherapy for lung metastasis and been treated with axitinib. Bronchoscopy revealed necrosis in the bronchi of the right middle and lower lobes. Culture of the necrotic bronchia...

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Autores principales: Nakatsumi, Hiroki, Watanabe, Satoshi, Gohara, Kazuki, Kobayashi, Takafumi, Takeda, Yoshihiro, Kasahara, Kazuo, Yano, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593151/
https://www.ncbi.nlm.nih.gov/pubmed/35228430
http://dx.doi.org/10.2169/internalmedicine.9143-21
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author Nakatsumi, Hiroki
Watanabe, Satoshi
Gohara, Kazuki
Kobayashi, Takafumi
Takeda, Yoshihiro
Kasahara, Kazuo
Yano, Seiji
author_facet Nakatsumi, Hiroki
Watanabe, Satoshi
Gohara, Kazuki
Kobayashi, Takafumi
Takeda, Yoshihiro
Kasahara, Kazuo
Yano, Seiji
author_sort Nakatsumi, Hiroki
collection PubMed
description A 38-year-old man with renal cell carcinoma was referred to our hospital because of a productive cough. He had received radiotherapy for lung metastasis and been treated with axitinib. Bronchoscopy revealed necrosis in the bronchi of the right middle and lower lobes. Culture of the necrotic bronchial specimen revealed methicillin-resistant Staphylococcus aureus (MRSA). Although radiotherapy in combination with axitinib carries a risk of causing airway toxicity, MRSA necrotizing bronchitis has not been reported. Physicians should consider the possibility of infectious necrotizing bronchitis if irradiated patients show prolonged respiratory symptoms.
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spelling pubmed-95931512022-11-07 Methicillin-resistant Staphylococcus aureus Necrotizing Bronchitis after Radiotherapy in Combination with Axitinib Nakatsumi, Hiroki Watanabe, Satoshi Gohara, Kazuki Kobayashi, Takafumi Takeda, Yoshihiro Kasahara, Kazuo Yano, Seiji Intern Med Case Report A 38-year-old man with renal cell carcinoma was referred to our hospital because of a productive cough. He had received radiotherapy for lung metastasis and been treated with axitinib. Bronchoscopy revealed necrosis in the bronchi of the right middle and lower lobes. Culture of the necrotic bronchial specimen revealed methicillin-resistant Staphylococcus aureus (MRSA). Although radiotherapy in combination with axitinib carries a risk of causing airway toxicity, MRSA necrotizing bronchitis has not been reported. Physicians should consider the possibility of infectious necrotizing bronchitis if irradiated patients show prolonged respiratory symptoms. The Japanese Society of Internal Medicine 2022-02-26 2022-10-01 /pmc/articles/PMC9593151/ /pubmed/35228430 http://dx.doi.org/10.2169/internalmedicine.9143-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nakatsumi, Hiroki
Watanabe, Satoshi
Gohara, Kazuki
Kobayashi, Takafumi
Takeda, Yoshihiro
Kasahara, Kazuo
Yano, Seiji
Methicillin-resistant Staphylococcus aureus Necrotizing Bronchitis after Radiotherapy in Combination with Axitinib
title Methicillin-resistant Staphylococcus aureus Necrotizing Bronchitis after Radiotherapy in Combination with Axitinib
title_full Methicillin-resistant Staphylococcus aureus Necrotizing Bronchitis after Radiotherapy in Combination with Axitinib
title_fullStr Methicillin-resistant Staphylococcus aureus Necrotizing Bronchitis after Radiotherapy in Combination with Axitinib
title_full_unstemmed Methicillin-resistant Staphylococcus aureus Necrotizing Bronchitis after Radiotherapy in Combination with Axitinib
title_short Methicillin-resistant Staphylococcus aureus Necrotizing Bronchitis after Radiotherapy in Combination with Axitinib
title_sort methicillin-resistant staphylococcus aureus necrotizing bronchitis after radiotherapy in combination with axitinib
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593151/
https://www.ncbi.nlm.nih.gov/pubmed/35228430
http://dx.doi.org/10.2169/internalmedicine.9143-21
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