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AMPK activation is sufficient to increase skeletal muscle glucose uptake and glycogen synthesis but is not required for contraction-mediated increases in glucose metabolism

The AMP-activated protein kinase (AMPK) is a cellular sensor of energetics and when activated in skeletal muscle during contraction can impart changes in skeletal muscle metabolism. Therapeutics that selectively activate AMPK have been developed to lower glucose levels through increased glucose disp...

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Detalles Bibliográficos
Autores principales: Esquejo, Ryan M., Albuquerque, Bina, Sher, Anna, Blatnik, Matthew, Wald, Kyle, Peloquin, Matthew, Delmore, Jake, Kindt, Erick, Li, Wenlin, Young, Jamey D., Cameron, Kim, Miller, Russell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593205/
https://www.ncbi.nlm.nih.gov/pubmed/36303906
http://dx.doi.org/10.1016/j.heliyon.2022.e11091

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