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Histone Deacetylase Inhibition Restores Behavioral and Synaptic Function in a Mouse Model of 16p11.2 Deletion
BACKGROUND: Microdeletion of the human 16p11.2 gene locus confers risk for autism spectrum disorders and intellectual disability. How 16p11.2 deletion is linked to these neurodevelopmental disorders and whether there are treatment avenues for the manifested phenotypes remain to be elucidated. Emergi...
Autores principales: | Wang, Wei, Tan, Tao, Cao, Qing, Zhang, Freddy, Rein, Benjamin, Duan, Wei-Ming, Yan, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593221/ https://www.ncbi.nlm.nih.gov/pubmed/35907244 http://dx.doi.org/10.1093/ijnp/pyac048 |
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