Improving Statistical Certainty of Glycosylation Similarity between Influenza A Virus Variants Using Data-Independent Acquisition Mass Spectrometry

Amino acid sequences of immunodominant domains of hemagglutinin (HA) on the surface of influenza A virus (IAV) evolve rapidly, producing viral variants. HA mediates receptor recognition, binding and cell entry, and serves as the target for IAV vaccines. Glycosylation, a post-translational modificati...

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Detalles Bibliográficos
Autores principales: Chang, Deborah, Klein, Joshua, Hackett, William E., Nalehua, Mary Rachel, Wan, Xiu-Feng, Zaia, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593740/
https://www.ncbi.nlm.nih.gov/pubmed/36103992
http://dx.doi.org/10.1016/j.mcpro.2022.100412

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