Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33α and TRIM33β Bromodomains

[Image: see text] TRIM33 is a member of the tripartite motif (TRIM) family of proteins, some of which possess E3 ligase activity and are involved in the ubiquitin-dependent degradation of proteins. Four of the TRIM family proteins, TRIM24 (TIF1α), TRIM28 (TIF1β), TRIM33 (TIF1γ) and TRIM66, contain C...

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Detalles Bibliográficos
Autores principales: Sekirnik, Angelina R., Reynolds, Jessica K., See, Larissa, Bluck, Joseph P., Scorah, Amy R., Tallant, Cynthia, Lee, Bernadette, Leszczynska, Katarzyna B., Grimley, Rachel L., Storer, R. Ian, Malattia, Marta, Crespillo, Sara, Caria, Sofia, Duclos, Stephanie, Hammond, Ester M., Knapp, Stefan, Morris, Garrett M., Duarte, Fernanda, Biggin, Philip C., Conway, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594046/
https://www.ncbi.nlm.nih.gov/pubmed/36098557
http://dx.doi.org/10.1021/acschembio.2c00266

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