Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin

[Image: see text] Langerin is a mammalian C-type lectin expressed on Langerhans cells in the skin. As an innate immune cell receptor, Langerin is involved in coordinating innate and adaptive immune responses against various incoming threats. We have previously reported a series of thiazolopyrimidine...

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Detalles Bibliográficos
Autores principales: Zhang, Hengxi, Modenutti, Carlos, Nekkanti, Yelha Phani Kumar, Denis, Maxime, Bermejo, Iris A., Lefèbre, Jonathan, Che, Kateryna, Kim, Dongyoon, Kagelmacher, Marten, Kurzbach, Dennis, Nazaré, Marc, Rademacher, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594047/
https://www.ncbi.nlm.nih.gov/pubmed/36153965
http://dx.doi.org/10.1021/acschembio.2c00626

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