Copper-catalyzed cross coupling reaction of sulfonyl hydrazides with 3-aminoindazoles

A novel Cu-catalyzed radical–radical cross coupling reaction of 3-aminoindazoles with sulfonyl hydrazides has been disclosed, enabling the production of diverse 1,3-substituted aminoindazoles in good yields. This methodology is distinguished by readily available starting materials, wide substrate sc...

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Autores principales: Feng, Guipeng, Meng, Jie, Xu, Shaohong, Gao, Yao, Zhu, Yingying, Huang, Ziyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594103/
https://www.ncbi.nlm.nih.gov/pubmed/36337965
http://dx.doi.org/10.1039/d2ra05956h
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author Feng, Guipeng
Meng, Jie
Xu, Shaohong
Gao, Yao
Zhu, Yingying
Huang, Ziyu
author_facet Feng, Guipeng
Meng, Jie
Xu, Shaohong
Gao, Yao
Zhu, Yingying
Huang, Ziyu
author_sort Feng, Guipeng
collection PubMed
description A novel Cu-catalyzed radical–radical cross coupling reaction of 3-aminoindazoles with sulfonyl hydrazides has been disclosed, enabling the production of diverse 1,3-substituted aminoindazoles in good yields. This methodology is distinguished by readily available starting materials, wide substrate scope and operational simplicity. In addition, a gram-scale reaction has been well demonstrated.
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spelling pubmed-95941032022-11-03 Copper-catalyzed cross coupling reaction of sulfonyl hydrazides with 3-aminoindazoles Feng, Guipeng Meng, Jie Xu, Shaohong Gao, Yao Zhu, Yingying Huang, Ziyu RSC Adv Chemistry A novel Cu-catalyzed radical–radical cross coupling reaction of 3-aminoindazoles with sulfonyl hydrazides has been disclosed, enabling the production of diverse 1,3-substituted aminoindazoles in good yields. This methodology is distinguished by readily available starting materials, wide substrate scope and operational simplicity. In addition, a gram-scale reaction has been well demonstrated. The Royal Society of Chemistry 2022-10-25 /pmc/articles/PMC9594103/ /pubmed/36337965 http://dx.doi.org/10.1039/d2ra05956h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Feng, Guipeng
Meng, Jie
Xu, Shaohong
Gao, Yao
Zhu, Yingying
Huang, Ziyu
Copper-catalyzed cross coupling reaction of sulfonyl hydrazides with 3-aminoindazoles
title Copper-catalyzed cross coupling reaction of sulfonyl hydrazides with 3-aminoindazoles
title_full Copper-catalyzed cross coupling reaction of sulfonyl hydrazides with 3-aminoindazoles
title_fullStr Copper-catalyzed cross coupling reaction of sulfonyl hydrazides with 3-aminoindazoles
title_full_unstemmed Copper-catalyzed cross coupling reaction of sulfonyl hydrazides with 3-aminoindazoles
title_short Copper-catalyzed cross coupling reaction of sulfonyl hydrazides with 3-aminoindazoles
title_sort copper-catalyzed cross coupling reaction of sulfonyl hydrazides with 3-aminoindazoles
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594103/
https://www.ncbi.nlm.nih.gov/pubmed/36337965
http://dx.doi.org/10.1039/d2ra05956h
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