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Assembly of a Ribozyme Ligase from Short Oligomers by Nonenzymatic Ligation
[Image: see text] Our current understanding of the chemistry of the primordial genetic material is fragmentary at best. The chemical replication of oligonucleotides long enough to perform catalytic functions is particularly problematic because of the low efficiency of nonenzymatic template copying....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594310/ https://www.ncbi.nlm.nih.gov/pubmed/32820909 http://dx.doi.org/10.1021/jacs.0c06722 |