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Synthetic Studies on Amphidinolide F: Exploration of Macrocycle Construction by Intramolecular Stille Coupling

[Image: see text] Exploration of an ambitious new strategy for the total synthesis of the cytotoxic marine natural product amphidinolide F is described, which features fabrication of the core structure from four readily accessible fragments and macrocycle construction through C9–C10 bond formation b...

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Detalles Bibliográficos
Autores principales: Decultot, Ludovic, Clark, J. Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594353/
https://www.ncbi.nlm.nih.gov/pubmed/36223230
http://dx.doi.org/10.1021/acs.orglett.2c03045