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Impact of the kidney transplantation moratorium in France because of the COVID-19 pandemic: Vincent Bonnemains
BACKGROUND: The COVID-19 pandemic has resulted in worldwide kidney transplantation (KT) moratoriums. The impacts of these moratoriums on the life expectancy of KT candidates remain unclear. METHODS: We simulated the evolution of several French candidate populations for KT using a multistate semi-Mar...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594415/ http://dx.doi.org/10.1093/eurpub/ckac130.224 |
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author | Bonnemains, V Le Borgne, F Savoye, E Legeai, C Pastural, M Bayat-Maokei, S Lenain, R Leffondré, K Couchoud, C Foucher, Y |
author_facet | Bonnemains, V Le Borgne, F Savoye, E Legeai, C Pastural, M Bayat-Maokei, S Lenain, R Leffondré, K Couchoud, C Foucher, Y |
author_sort | Bonnemains, V |
collection | PubMed |
description | BACKGROUND: The COVID-19 pandemic has resulted in worldwide kidney transplantation (KT) moratoriums. The impacts of these moratoriums on the life expectancy of KT candidates remain unclear. METHODS: We simulated the evolution of several French candidate populations for KT using a multistate semi-Markovian approach and according to moratorium durations ranging from 0 to 24 months. The transition rates were modeled from the 63,927 French patients who began dialysis or were registered on the waiting list for KT between 2011 and 2019. RESULTS: Among the 8,350 patients active on the waiting list at the time of the French KT moratorium decided on March 16, 2020, for 2.5-months, we predicted 4.0 additional months [CI: 2.8, 5.0] on the waiting list and 42 additional deaths [CI: -70, 150] up to March 16, 2030. In this population, we reported a significant impact for a 9-month moratorium duration: 135 attributable deaths [CI: 31, 257] up to March 16, 2030. Patients who became active on the list after March 2020 were less impacted. INTERPRETATION: The temporary moratorium of KT during a COVID-19 peak in order to free up hospitals’ resources doesn't impact patients’ 10-year survival if the moratorium does not exceed a prolonged period. Funding. French National Research Agency (ANR-20-COV8-0002-01). KEY MESSAGES: The French 2020 KT moratorium didn't impair patients’ 10-years survival. 9-month or longer moratoriums may impair patients’ 10-years survival. |
format | Online Article Text |
id | pubmed-9594415 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-95944152022-11-04 Impact of the kidney transplantation moratorium in France because of the COVID-19 pandemic: Vincent Bonnemains Bonnemains, V Le Borgne, F Savoye, E Legeai, C Pastural, M Bayat-Maokei, S Lenain, R Leffondré, K Couchoud, C Foucher, Y Eur J Public Health Poster Walks BACKGROUND: The COVID-19 pandemic has resulted in worldwide kidney transplantation (KT) moratoriums. The impacts of these moratoriums on the life expectancy of KT candidates remain unclear. METHODS: We simulated the evolution of several French candidate populations for KT using a multistate semi-Markovian approach and according to moratorium durations ranging from 0 to 24 months. The transition rates were modeled from the 63,927 French patients who began dialysis or were registered on the waiting list for KT between 2011 and 2019. RESULTS: Among the 8,350 patients active on the waiting list at the time of the French KT moratorium decided on March 16, 2020, for 2.5-months, we predicted 4.0 additional months [CI: 2.8, 5.0] on the waiting list and 42 additional deaths [CI: -70, 150] up to March 16, 2030. In this population, we reported a significant impact for a 9-month moratorium duration: 135 attributable deaths [CI: 31, 257] up to March 16, 2030. Patients who became active on the list after March 2020 were less impacted. INTERPRETATION: The temporary moratorium of KT during a COVID-19 peak in order to free up hospitals’ resources doesn't impact patients’ 10-year survival if the moratorium does not exceed a prolonged period. Funding. French National Research Agency (ANR-20-COV8-0002-01). KEY MESSAGES: The French 2020 KT moratorium didn't impair patients’ 10-years survival. 9-month or longer moratoriums may impair patients’ 10-years survival. Oxford University Press 2022-10-25 /pmc/articles/PMC9594415/ http://dx.doi.org/10.1093/eurpub/ckac130.224 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the European Public Health Association. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Poster Walks Bonnemains, V Le Borgne, F Savoye, E Legeai, C Pastural, M Bayat-Maokei, S Lenain, R Leffondré, K Couchoud, C Foucher, Y Impact of the kidney transplantation moratorium in France because of the COVID-19 pandemic: Vincent Bonnemains |
title | Impact of the kidney transplantation moratorium in France because of the COVID-19 pandemic: Vincent Bonnemains |
title_full | Impact of the kidney transplantation moratorium in France because of the COVID-19 pandemic: Vincent Bonnemains |
title_fullStr | Impact of the kidney transplantation moratorium in France because of the COVID-19 pandemic: Vincent Bonnemains |
title_full_unstemmed | Impact of the kidney transplantation moratorium in France because of the COVID-19 pandemic: Vincent Bonnemains |
title_short | Impact of the kidney transplantation moratorium in France because of the COVID-19 pandemic: Vincent Bonnemains |
title_sort | impact of the kidney transplantation moratorium in france because of the covid-19 pandemic: vincent bonnemains |
topic | Poster Walks |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594415/ http://dx.doi.org/10.1093/eurpub/ckac130.224 |
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