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S-glutathionylation of Hsp90 enhances its degradation and correlates with favorable prognosis of breast cancer
Heat shock protein 90 (Hsp90) is a ubiquitous chaperone to interact with numerous proteins to regulate multiple cellular processes, especially during cell proliferation and cell cycle progression. Hsp90 exists in a high level in tumor cells and tissues, and thus serves as a prognostic biomarker or t...
Autores principales: | Shih, Yu-Yin, Lin, Hsien-Ya, Jan, Hau-Ming, Chen, Yu-Ju, Ong, Lih-Lih, Yu, Alice Lin-Tsing, Lin, Chun-Hung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594641/ https://www.ncbi.nlm.nih.gov/pubmed/36279628 http://dx.doi.org/10.1016/j.redox.2022.102501 |
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