Development of a modular photoreactor for the upscaling of continuous flow photochemistry

The upscaling of biphasic photochemical reactions is challenging because of the inherent constraints of liquid–gas mixing and light penetration. Using semi-permeable coaxial flow chemistry within a modular photoreactor, the photooxidation of the platform chemical furfural was scaled up to produce ro...

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Autores principales: Hermens, Johannes G. H., Lepage, Mathieu L., Kloekhorst, Arjan, Keller, Erik, Bloem, Robin, Meijer, Maurice, Feringa, Ben L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594834/
https://www.ncbi.nlm.nih.gov/pubmed/36352841
http://dx.doi.org/10.1039/d2re00310d
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author Hermens, Johannes G. H.
Lepage, Mathieu L.
Kloekhorst, Arjan
Keller, Erik
Bloem, Robin
Meijer, Maurice
Feringa, Ben L.
author_facet Hermens, Johannes G. H.
Lepage, Mathieu L.
Kloekhorst, Arjan
Keller, Erik
Bloem, Robin
Meijer, Maurice
Feringa, Ben L.
author_sort Hermens, Johannes G. H.
collection PubMed
description The upscaling of biphasic photochemical reactions is challenging because of the inherent constraints of liquid–gas mixing and light penetration. Using semi-permeable coaxial flow chemistry within a modular photoreactor, the photooxidation of the platform chemical furfural was scaled up to produce routinely 29 gram per day of biobased building block hydroxybutenolide, a precursor to acrylate alternatives.
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spelling pubmed-95948342022-11-07 Development of a modular photoreactor for the upscaling of continuous flow photochemistry Hermens, Johannes G. H. Lepage, Mathieu L. Kloekhorst, Arjan Keller, Erik Bloem, Robin Meijer, Maurice Feringa, Ben L. React Chem Eng Chemistry The upscaling of biphasic photochemical reactions is challenging because of the inherent constraints of liquid–gas mixing and light penetration. Using semi-permeable coaxial flow chemistry within a modular photoreactor, the photooxidation of the platform chemical furfural was scaled up to produce routinely 29 gram per day of biobased building block hydroxybutenolide, a precursor to acrylate alternatives. The Royal Society of Chemistry 2022-09-28 /pmc/articles/PMC9594834/ /pubmed/36352841 http://dx.doi.org/10.1039/d2re00310d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Hermens, Johannes G. H.
Lepage, Mathieu L.
Kloekhorst, Arjan
Keller, Erik
Bloem, Robin
Meijer, Maurice
Feringa, Ben L.
Development of a modular photoreactor for the upscaling of continuous flow photochemistry
title Development of a modular photoreactor for the upscaling of continuous flow photochemistry
title_full Development of a modular photoreactor for the upscaling of continuous flow photochemistry
title_fullStr Development of a modular photoreactor for the upscaling of continuous flow photochemistry
title_full_unstemmed Development of a modular photoreactor for the upscaling of continuous flow photochemistry
title_short Development of a modular photoreactor for the upscaling of continuous flow photochemistry
title_sort development of a modular photoreactor for the upscaling of continuous flow photochemistry
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594834/
https://www.ncbi.nlm.nih.gov/pubmed/36352841
http://dx.doi.org/10.1039/d2re00310d
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