Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life

We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months of age. Antibody increases after 3 months suggested natural infections. This information could guide the timing of f...

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Detalles Bibliográficos
Autores principales: Vielot, Nadja A, Brinkman, Amanda, DeMaso, Christina, Vilchez, Samuel, Lindesmith, Lisa C, Bucardo, Filemon, Reyes, Yaoska, Baric, Ralph S, Ryan, Elizabeth P, Braun, Ralph, Becker-Dreps, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595050/
https://www.ncbi.nlm.nih.gov/pubmed/35849145
http://dx.doi.org/10.1093/jpids/piac067
Descripción
Sumario:We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months of age. Antibody increases after 3 months suggested natural infections. This information could guide the timing of future norovirus vaccines.

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