Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life

We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months of age. Antibody increases after 3 months suggested natural infections. This information could guide the timing of f...

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Autores principales: Vielot, Nadja A, Brinkman, Amanda, DeMaso, Christina, Vilchez, Samuel, Lindesmith, Lisa C, Bucardo, Filemon, Reyes, Yaoska, Baric, Ralph S, Ryan, Elizabeth P, Braun, Ralph, Becker-Dreps, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595050/
https://www.ncbi.nlm.nih.gov/pubmed/35849145
http://dx.doi.org/10.1093/jpids/piac067
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author Vielot, Nadja A
Brinkman, Amanda
DeMaso, Christina
Vilchez, Samuel
Lindesmith, Lisa C
Bucardo, Filemon
Reyes, Yaoska
Baric, Ralph S
Ryan, Elizabeth P
Braun, Ralph
Becker-Dreps, Sylvia
author_facet Vielot, Nadja A
Brinkman, Amanda
DeMaso, Christina
Vilchez, Samuel
Lindesmith, Lisa C
Bucardo, Filemon
Reyes, Yaoska
Baric, Ralph S
Ryan, Elizabeth P
Braun, Ralph
Becker-Dreps, Sylvia
author_sort Vielot, Nadja A
collection PubMed
description We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months of age. Antibody increases after 3 months suggested natural infections. This information could guide the timing of future norovirus vaccines.
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spelling pubmed-95950502023-02-09 Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life Vielot, Nadja A Brinkman, Amanda DeMaso, Christina Vilchez, Samuel Lindesmith, Lisa C Bucardo, Filemon Reyes, Yaoska Baric, Ralph S Ryan, Elizabeth P Braun, Ralph Becker-Dreps, Sylvia J Pediatric Infect Dis Soc Brief Reports We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months of age. Antibody increases after 3 months suggested natural infections. This information could guide the timing of future norovirus vaccines. Oxford University Press 2022-07-18 /pmc/articles/PMC9595050/ /pubmed/35849145 http://dx.doi.org/10.1093/jpids/piac067 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Vielot, Nadja A
Brinkman, Amanda
DeMaso, Christina
Vilchez, Samuel
Lindesmith, Lisa C
Bucardo, Filemon
Reyes, Yaoska
Baric, Ralph S
Ryan, Elizabeth P
Braun, Ralph
Becker-Dreps, Sylvia
Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life
title Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life
title_full Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life
title_fullStr Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life
title_full_unstemmed Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life
title_short Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life
title_sort breadth and dynamics of human norovirus-specific antibodies in the first year of life
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595050/
https://www.ncbi.nlm.nih.gov/pubmed/35849145
http://dx.doi.org/10.1093/jpids/piac067
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