Primary tumor–derived systemic nANGPTL4 inhibits metastasis

Primary tumors and distant site metastases form a bidirectionally communicating system. Yet, the molecular mechanisms of this crosstalk are poorly understood. Here, we identified the proteolytically cleaved fragments of angiopoietin-like 4 (ANGPTL4) as contextually active protumorigenic and antitumo...

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Detalles Bibliográficos
Autores principales: Hübers, Corinne, Abdul Pari, Ashik Ahmed, Grieshober, Denise, Petkov, Martin, Schmidt, Alexander, Messmer, Tatjana, Heyer, Christian Moritz, Schölch, Sebastian, Kapel, Stephanie S., Gengenbacher, Nicolas, Singhal, Mahak, Schieb, Benjamin, Fricke, Claudine, Will, Rainer, Remans, Kim, Utikal, Jochen Sven, Reissfelder, Christoph, Schlesner, Matthias, Hodivala-Dilke, Kairbaan M., Kersten, Sander, Goerdt, Sergij, Augustin, Hellmut G., Felcht, Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595206/
https://www.ncbi.nlm.nih.gov/pubmed/36269299
http://dx.doi.org/10.1084/jem.20202595

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