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Blood–Brain Barrier Disruption in Preclinical Mouse Models of Stroke Can Be an Experimental Artifact Caused by Craniectomy
The pathophysiological features of ischemia-related blood–brain barrier (BBB) disruption are widely studied using preclinical stroke models. However, in many of these models, craniectomy is required to confirm arterial occlusion via laser Doppler flowmetry or to enable direct ligation of the cerebra...
Autores principales: | Liu, Che-Wei, Wang, Eric Yuhsiang, Wang, Hwai-Lee, Liao, Kate Hsiurong, Chen, Hsiao-Yun, Chen, Hank Szuhan, Lai, Ted Weita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595391/ https://www.ncbi.nlm.nih.gov/pubmed/36224001 http://dx.doi.org/10.1523/ENEURO.0343-22.2022 |
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