A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling

Many breast cancer (BC) patients suffer from complications of metastatic disease. To form metastases, cancer cells must become migratory and coordinate both invasive and proliferative programs at distant organs. Here, we identify srGAP1 as a regulator of a proliferative-to-invasive switch in BC cell...

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Detalles Bibliográficos
Autores principales: Mondal, Chandrani, Gacha-Garay, Majo J., Larkin, Kathryn A., Adikes, Rebecca C., Di Martino, Julie S., Chien, Chen-Chi, Fraser, Madison, Eni-aganga, Ireti, Agullo-Pascual, Esperanza, Cialowicz, Katarzyna, Ozbek, Umut, Naba, Alexandra, Gaitas, Angelo, Fu, Tian-Ming, Upadhyayula, Srigokul, Betzig, Eric, Matus, David Q., Martin, Benjamin L., Bravo-Cordero, Jose Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596226/
https://www.ncbi.nlm.nih.gov/pubmed/36130489
http://dx.doi.org/10.1016/j.celrep.2022.111358

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