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Cardiac Troponin T in Neonates from Normal and Gestational Diabetes Mellitus Pregnancy

This study is aimed at testing the hypothesis that serum analysis of high-sensitivity troponin T in neonates may serve as a diagnostic tool to predict the risk of gestational diabetes mellitus (GDM). 86 newborns were studied and stratified into two groups: healthy group; newborns with body weight ≥...

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Autores principales: Kłaczewska, Joanna, Tomasiuk, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596251/
https://www.ncbi.nlm.nih.gov/pubmed/36303588
http://dx.doi.org/10.1155/2022/6171687
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author Kłaczewska, Joanna
Tomasiuk, Ryszard
author_facet Kłaczewska, Joanna
Tomasiuk, Ryszard
author_sort Kłaczewska, Joanna
collection PubMed
description This study is aimed at testing the hypothesis that serum analysis of high-sensitivity troponin T in neonates may serve as a diagnostic tool to predict the risk of gestational diabetes mellitus (GDM). 86 newborns were studied and stratified into two groups: healthy group; newborns with body weight ≥ 10th percentile, born in good condition (APG 8-10pts) of pregnancy not complicated by diabetes, and the GDM group; neonates born to mothers with type 1 or type 2 diabetes. Results. The study revealed minimal troponin levels in GDM, and healthy groups equal to 0.02 ng/mL and 0.028 ng/mL, respectively. The GDM group is defined by an interquartile range of hs-TnT higher than the healthy group. This study confirms previously reported upper levels of troponin in healthy children. There are possible health problems that can appear during infancy and influence the further development of a child affected by GDM.
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spelling pubmed-95962512022-10-26 Cardiac Troponin T in Neonates from Normal and Gestational Diabetes Mellitus Pregnancy Kłaczewska, Joanna Tomasiuk, Ryszard Biomed Res Int Research Article This study is aimed at testing the hypothesis that serum analysis of high-sensitivity troponin T in neonates may serve as a diagnostic tool to predict the risk of gestational diabetes mellitus (GDM). 86 newborns were studied and stratified into two groups: healthy group; newborns with body weight ≥ 10th percentile, born in good condition (APG 8-10pts) of pregnancy not complicated by diabetes, and the GDM group; neonates born to mothers with type 1 or type 2 diabetes. Results. The study revealed minimal troponin levels in GDM, and healthy groups equal to 0.02 ng/mL and 0.028 ng/mL, respectively. The GDM group is defined by an interquartile range of hs-TnT higher than the healthy group. This study confirms previously reported upper levels of troponin in healthy children. There are possible health problems that can appear during infancy and influence the further development of a child affected by GDM. Hindawi 2022-10-18 /pmc/articles/PMC9596251/ /pubmed/36303588 http://dx.doi.org/10.1155/2022/6171687 Text en Copyright © 2022 Joanna Kłaczewska and Ryszard Tomasiuk. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kłaczewska, Joanna
Tomasiuk, Ryszard
Cardiac Troponin T in Neonates from Normal and Gestational Diabetes Mellitus Pregnancy
title Cardiac Troponin T in Neonates from Normal and Gestational Diabetes Mellitus Pregnancy
title_full Cardiac Troponin T in Neonates from Normal and Gestational Diabetes Mellitus Pregnancy
title_fullStr Cardiac Troponin T in Neonates from Normal and Gestational Diabetes Mellitus Pregnancy
title_full_unstemmed Cardiac Troponin T in Neonates from Normal and Gestational Diabetes Mellitus Pregnancy
title_short Cardiac Troponin T in Neonates from Normal and Gestational Diabetes Mellitus Pregnancy
title_sort cardiac troponin t in neonates from normal and gestational diabetes mellitus pregnancy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596251/
https://www.ncbi.nlm.nih.gov/pubmed/36303588
http://dx.doi.org/10.1155/2022/6171687
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