GPC3-Unc5 receptor complex structure and role in cell migration

Neural migration is a critical step during brain development that requires the interactions of cell-surface guidance receptors. Cancer cells often hijack these mechanisms to disseminate. Here, we reveal crystal structures of Uncoordinated-5 receptor D (Unc5D) in complex with morphogen receptor glypi...

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Detalles Bibliográficos
Autores principales: Akkermans, Onno, Delloye-Bourgeois, Céline, Peregrina, Claudia, Carrasquero-Ordaz, Maria, Kokolaki, Maria, Berbeira-Santana, Miguel, Chavent, Matthieu, Reynaud, Florie, Raj, Ritu, Agirre, Jon, Aksu, Metin, White, Eleanor S., Lowe, Edward, Ben Amar, Dounia, Zaballa, Sofia, Huo, Jiandong, Pakos, Irene, McCubbin, Patrick T.N., Comoletti, Davide, Owens, Raymond J., Robinson, Carol V., Castellani, Valérie, del Toro, Daniel, Seiradake, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596381/
https://www.ncbi.nlm.nih.gov/pubmed/36240740
http://dx.doi.org/10.1016/j.cell.2022.09.025

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