Gene expression-based dissection of inter-histotypes, intra-histotype and intra-tumor heterogeneity in pediatric tumors

Intra-tumor heterogeneity (ITH) fosters tumor evolution, resistance to therapy, and relapse. Recently, many evidence have been accumulated on the occurrence of genetic ITH in pediatric cancers. With this study we aimed to address the downstream effects that genetic and epigenetic ITH, and tumor-micr...

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Detalles Bibliográficos
Autores principales: Ciceri, Sara, Carenzo, Andrea, Iannó, Maria Federica, Bertolotti, Alessia, Morosi, Carlo, Luksch, Roberto, Spreafico, Filippo, Collini, Paola, Radice, Paolo, Massimino, Maura, De Cecco, Loris, Perotti, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596396/
https://www.ncbi.nlm.nih.gov/pubmed/36284197
http://dx.doi.org/10.1038/s41598-022-20536-6

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