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CHK2 activation contributes to the development of oxaliplatin resistance in colorectal cancer

BACKGROUND: Colorectal cancer (CRC), the most common cancer type, causes high morbidity and mortality. Patients who develop drug resistance to oxaliplatin-based regimens have short overall survival. Thus, identifying molecules involved in the development of oxaliplatin resistance is critical for des...

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Detalles Bibliográficos
Autores principales:	Hsieh, Chi-Che, Hsu, Sen-Huei, Lin, Chih-Yu, Liaw, Hung-Jiun, Li, Ting-Wei, Jiang, Kuan-Ying, Chiang, Nai-Jung, Chen, Shang-Hung, Lin, Bo-Wen, Chen, Po-Chuan, Chan, Ren-Hao, Lin, Peng-Chan, Yeh, Yu-Min, Shen, Che-Hung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596403/ https://www.ncbi.nlm.nih.gov/pubmed/35999268 http://dx.doi.org/10.1038/s41416-022-01946-9

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