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Binary-FRET reveals transient excited-state structure associated with activity-dependent CaMKII - NR2B binding and adaptation

Synaptic functions are mediated and modulated by a coordinated choreography of protein conformational changes and interactions in response to intracellular calcium dynamics. Time-lapse Förster resonance energy transfer can be used to study the dynamics of both conformational changes and protein-prot...

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Detalles Bibliográficos
Autores principales: Nguyen, Tuan A., Puhl, Henry L., Hines, Kirk, Liput, Daniel J., Vogel, Steven S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596428/
https://www.ncbi.nlm.nih.gov/pubmed/36284097
http://dx.doi.org/10.1038/s41467-022-33795-8