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Basal Gp78-dependent mitophagy promotes mitochondrial health and limits mitochondrial ROS
Mitochondria are major sources of cytotoxic reactive oxygen species (ROS), such as superoxide and hydrogen peroxide, that when uncontrolled contribute to cancer progression. Maintaining a finely tuned, healthy mitochondrial population is essential for cellular homeostasis and survival. Mitophagy, th...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596570/ https://www.ncbi.nlm.nih.gov/pubmed/36284011 http://dx.doi.org/10.1007/s00018-022-04585-8 |