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Suppression of trinucleotide repeat expansion in spermatogenic cells in Huntington’s disease

Trinucleotide repeats (TNRs) are dispersed throughout the human genome. About 20 loci are related to human diseases, such as Huntington’s disease (HD). A larger TNR instability is predominantly observed in the paternal germ cells in some TNR disorders. Suppressing the expansion during spermatogenesi...

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Detalles Bibliográficos
Autores principales:	Cho, In K., Easley, Charles A., Chan, Anthony W. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596677/ https://www.ncbi.nlm.nih.gov/pubmed/36066723 http://dx.doi.org/10.1007/s10815-022-02594-x

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