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Metformin ameliorates olanzapine-induced obesity and glucose intolerance by regulating hypothalamic inflammation and microglial activation in female mice
Olanzapine (OLZ), a widely used second-generation antipsychotic drug, is known to cause metabolic side effects, including diabetes and obesity. Interestingly, OLZ-induced metabolic side effects have been demonstrated to be more profound in females in human studies and animal models. Metformin (MET)...
Autores principales: | Suh, Sang Bum, Lee, Nayoung, Kim, Jaedeok, Kim, Saeha, Jang, Sooyeon, Park, Jong Kook, Lee, Keunwook, Choi, Soo Young, Kwon, Hyung-Joo, Lee, Chan Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596779/ https://www.ncbi.nlm.nih.gov/pubmed/36313357 http://dx.doi.org/10.3389/fphar.2022.906717 |
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