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Establishment and large-scale validation of a three-dimensional tumor model on an array chip for anticancer drug evaluation

Two-dimensional (2D) tumor model has always poorly predicted drug response of animal model due to the lack of recapitulation of tumor microenvironment. Establishing a biomimetic, controllable, and cost-effective three-dimensional (3D) model and large-scale validation of its in vivo predictivity has...

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Detalles Bibliográficos
Autores principales: Xiao, Rong-Rong, Jin, Lei, Xie, Nan, Luo, Piaopiao, Gao, Wenjie, Tu, Pengfei, Ai, Xiaoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596801/
https://www.ncbi.nlm.nih.gov/pubmed/36313330
http://dx.doi.org/10.3389/fphar.2022.1032975