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Functional Phosphoproteomics in Cancer Chemoresistance Using CRISPR‐Mediated Base Editors
Selective inhibition of targeted protein kinases is an effective therapeutic approach for treatment of human malignancies, which interferes phosphorylation of cellular substrates. However, a drug‐imposed selection creates pressures for tumor cells to acquire chemoresistance‐conferring mutations or a...
Autores principales: | Li, Jianan, Lin, Jianxiang, Huang, Shisheng, Li, Min, Yu, Wenxia, Zhao, Yuting, Guo, Junfan, Zhang, Pumin, Huang, Xingxu, Qiao, Yunbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596822/ https://www.ncbi.nlm.nih.gov/pubmed/36045417 http://dx.doi.org/10.1002/advs.202200717 |
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