cGAS-STING pathway targeted therapies and their applications in the treatment of high-grade glioma

Median survival of patients with glioblastoma (GBM) treated with standard of care which consists of maximal safe resection of the contrast-enhancing portion of the tumor followed by radiation therapy with concomitant adjuvant temozolomide (TMZ) remains 15 months. The tumor microenvironment (TME) is...

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Detalles Bibliográficos
Autores principales: Tripathi, Shashwat, Najem, Hinda, Mahajan, Akanksha Sanjay, Zhang, Peng, Low, Justin T, Stegh, Alexander H, Curran, Michael A, Ashley, David M, James, Charles David, Heimberger, Amy B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597127/
https://www.ncbi.nlm.nih.gov/pubmed/36324813
http://dx.doi.org/10.12688/f1000research.125163.1

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