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Lysosomal positioning diseases: beyond substrate storage
Lysosomal storage diseases (LSDs) comprise a group of inherited monogenic disorders characterized by lysosomal dysfunctions due to undegraded substrate accumulation. They are caused by a deficiency in specific lysosomal hydrolases involved in cellular catabolism, or non-enzymatic proteins essential...
Autores principales: | Scerra, Gianluca, De Pasquale, Valeria, Scarcella, Melania, Caporaso, Maria Gabriella, Pavone, Luigi Michele, D'Agostino, Massimo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597170/ https://www.ncbi.nlm.nih.gov/pubmed/36285443 http://dx.doi.org/10.1098/rsob.220155 |
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