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Locally correlated kinetics of post-replication DNA methylation reveals processivity and region specificity in DNA methylation maintenance

DNA methylation occurs predominantly on cytosine-phosphate-guanine (CpG) dinucleotides in the mammalian genome, and the methylation landscape is maintained over mitotic cell division. It has been posited that coupling of maintenance methylation activity among neighbouring CpGs is critical to stabili...

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Detalles Bibliográficos
Autores principales:	Ren, Honglei, Taylor, Robert B., Downing, Timothy L., Read, Elizabeth L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2022
Materias:	Life Sciences–Physics interface
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597173/ https://www.ncbi.nlm.nih.gov/pubmed/36285438 http://dx.doi.org/10.1098/rsif.2022.0415

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