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Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.)
Plant polyphenol supplementation may improve fish health in aquaculture systems. To assess the potential benefits and function mechanism of plant polyphenols in aquaculture, fish were fed either basal feed (CON) or the basal feed supplemented with 500 mg/kg of curcumin (CUR), oligomeric proanthocyan...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597254/ https://www.ncbi.nlm.nih.gov/pubmed/36312947 http://dx.doi.org/10.3389/fmicb.2022.977292 |
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author | Zhang, Rong Kang, Xin Liu, Lili Wang, Xiaowen Li, Huijuan Zhu, Jianya Cao, Yongchun Zhu, Hua |
author_facet | Zhang, Rong Kang, Xin Liu, Lili Wang, Xiaowen Li, Huijuan Zhu, Jianya Cao, Yongchun Zhu, Hua |
author_sort | Zhang, Rong |
collection | PubMed |
description | Plant polyphenol supplementation may improve fish health in aquaculture systems. To assess the potential benefits and function mechanism of plant polyphenols in aquaculture, fish were fed either basal feed (CON) or the basal feed supplemented with 500 mg/kg of curcumin (CUR), oligomeric proanthocyanidins (OPC), chlorogenic acid (CGA), or resveratrol (RES). After an 8-week feeding experiment, blood samples were used to analyze the concentrations of biochemical indices. Gut samples were collected to evaluate microbiota, short chain fatty acid (SCFA) levels, and gene expression. The results indicated that polyphenol administration reduced serum glucose and insulin. Lysozyme activity was enhanced by OPC and CGA, and superoxide dismutase activity was increased by CUR, OPC, and CGA. The gut microbial structure of the RES group was segregated from that of the CON, and the genus Bacteroides was identified as a potential biomarker in the CUR, CGA, and RES groups. Total gut SCFA increased in the CUR, CGA, and RES groups. A strong correlation was observed between Bacteroides and SCFA. In conclusion, dietary polyphenols have distinct anti-inflammatory, anti-oxidant, and anti-hyperglycemic activities that may be closely associated with their microbiota-modulation effects. |
format | Online Article Text |
id | pubmed-9597254 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95972542022-10-27 Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) Zhang, Rong Kang, Xin Liu, Lili Wang, Xiaowen Li, Huijuan Zhu, Jianya Cao, Yongchun Zhu, Hua Front Microbiol Microbiology Plant polyphenol supplementation may improve fish health in aquaculture systems. To assess the potential benefits and function mechanism of plant polyphenols in aquaculture, fish were fed either basal feed (CON) or the basal feed supplemented with 500 mg/kg of curcumin (CUR), oligomeric proanthocyanidins (OPC), chlorogenic acid (CGA), or resveratrol (RES). After an 8-week feeding experiment, blood samples were used to analyze the concentrations of biochemical indices. Gut samples were collected to evaluate microbiota, short chain fatty acid (SCFA) levels, and gene expression. The results indicated that polyphenol administration reduced serum glucose and insulin. Lysozyme activity was enhanced by OPC and CGA, and superoxide dismutase activity was increased by CUR, OPC, and CGA. The gut microbial structure of the RES group was segregated from that of the CON, and the genus Bacteroides was identified as a potential biomarker in the CUR, CGA, and RES groups. Total gut SCFA increased in the CUR, CGA, and RES groups. A strong correlation was observed between Bacteroides and SCFA. In conclusion, dietary polyphenols have distinct anti-inflammatory, anti-oxidant, and anti-hyperglycemic activities that may be closely associated with their microbiota-modulation effects. Frontiers Media S.A. 2022-10-12 /pmc/articles/PMC9597254/ /pubmed/36312947 http://dx.doi.org/10.3389/fmicb.2022.977292 Text en Copyright © 2022 Zhang, Kang, Liu, Wang, Li, Zhu, Cao and Zhu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Microbiology Zhang, Rong Kang, Xin Liu, Lili Wang, Xiaowen Li, Huijuan Zhu, Jianya Cao, Yongchun Zhu, Hua Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) |
title | Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) |
title_full | Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) |
title_fullStr | Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) |
title_full_unstemmed | Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) |
title_short | Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) |
title_sort | gut microbiota modulation by plant polyphenols in koi carp (cyprinus carpio l.) |
topic | Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597254/ https://www.ncbi.nlm.nih.gov/pubmed/36312947 http://dx.doi.org/10.3389/fmicb.2022.977292 |
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