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Target engagement of ginsenosides in mild cognitive impairment using mass spectrometry-based drug affinity responsive target stability
BACKGROUND: Mild cognitive impairment (MCI) is a transitional condition between normality and dementia. Ginseng is known to have effects on attenuating cognitive deficits in neurogenerative diseases. Ginsenosides are the main bioactive component of ginseng, and their protein targets have not been fu...
Autores principales: | Zhu, Zhu, Li, Ruimei, Qin, Wei, Zhang, Hantao, Cheng, Yao, Chen, Feiyan, Chen, Cuihua, Chen, Lin, Zhao, Yunan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597435/ https://www.ncbi.nlm.nih.gov/pubmed/36312734 http://dx.doi.org/10.1016/j.jgr.2021.12.003 |
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