Ginsengenin derivatives synthesized from 20(R)-panaxotriol: Synthesis, characterization, and antitumor activity targeting HIF-1 pathway

BACKGROUND: Ginseng possesses antitumor effects, and ginsenosides are considered to be one of its main active chemical components. Ginsenosides can further be hydrolyzed to generate secondary saponins, and 20(R)-panaxotriol is an important sapogenin of ginsenosides. We aimed to synthesize a new gins...

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Detalles Bibliográficos
Autores principales: Guo, Hong-Yan, Xing, Yue, Sun, Yu-Qiao, Liu, Can, Xu, Qian, Shang, Fan-Fan, Zhang, Run-Hui, Jin, Xue-Jun, Chen, Fener, Lee, Jung Joon, Kang, Dongzhou, Shen, Qing-Kun, Quan, Zhe-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597438/
https://www.ncbi.nlm.nih.gov/pubmed/36312731
http://dx.doi.org/10.1016/j.jgr.2022.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597438/
https://www.ncbi.nlm.nih.gov/pubmed/36312731
http://dx.doi.org/10.1016/j.jgr.2022.03.001

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