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Age, brain region, and gene dosage-differential transcriptomic changes in Shank3-mutant mice

Shank3 is an abundant excitatory postsynaptic scaffolding protein implicated in various neurodevelopmental disorders, including autism spectrum disorder (ASD), Phelan-McDermid syndrome, intellectual disability, and schizophrenia. Shank3-mutant mice show various molecular, synaptic, and behavioral de...

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Detalles Bibliográficos
Autores principales:	Yoo, Taesun, Yoo, Ye-Eun, Kang, Hyojin, Kim, Eunjoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597470/ https://www.ncbi.nlm.nih.gov/pubmed/36311023 http://dx.doi.org/10.3389/fnmol.2022.1017512

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