Saponin attenuates diesel exhaust particle (DEP)-induced MUC5AC expression and pro-inflammatory cytokine upregulation via TLR4/TRIF/NF-κB signaling pathway in airway epithelium and ovalbumin (OVA)-sensitized mice

BACKGROUND: Diesel exhaust particle (DEP) is a harmful kind of particulate matter known to exacerbate pre-existing respiratory diseases. Although their adverse effects on airway pathologies have been widely studied, the mechanistic analysis of signaling pathways and potential targets in reducing DEP...

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Detalles Bibliográficos
Autores principales: Jo, Sooyeon, Na, Hyung Gyun, Choi, Yoon Seok, Bae, Chang Hoon, Song, Si-Youn, Kim, Yong-Dae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597484/
https://www.ncbi.nlm.nih.gov/pubmed/36312733
http://dx.doi.org/10.1016/j.jgr.2022.03.009

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