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CRISPR-Cas9-mediated functional dissection of the foxc1 genomic region in zebrafish identifies critical conserved cis-regulatory elements

FOXC1 encodes a forkhead-domain transcription factor associated with several ocular disorders. Correct FOXC1 dosage is critical to normal development, yet the mechanisms controlling its expression remain unknown. Together with FOXQ1 and FOXF2, FOXC1 is part of a cluster of FOX genes conserved in ver...

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Detalles Bibliográficos
Autores principales:	Ferre-Fernández, Jesús-José, Muheisen, Sanaa, Thompson, Samuel, Semina, Elena V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597995/ https://www.ncbi.nlm.nih.gov/pubmed/36284357 http://dx.doi.org/10.1186/s40246-022-00423-x

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