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Genetic and epigenetic regulation of Catechol-O-methyltransferase in relation to inflammation in chronic fatigue syndrome and Fibromyalgia

BACKGROUND: Catechol-O-methyltransferase (COMT) has been shown to influence clinical pain, descending modulation, and exercise-induced symptom worsening. COMT regulates nociceptive processing and inflammation, key pathophysiological features of Chronic Fatigue Syndrome and Fibromyalgia (CFS/FM). We...

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Detalles Bibliográficos
Autores principales:	Polli, Andrea, Hendrix, Jolien, Ickmans, Kelly, Bakusic, Jelena, Ghosh, Manosij, Monteyne, Dora, Velkeniers, Brigitte, Bekaert, Bram, Nijs, Jo, Godderis, Lode
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598022/ https://www.ncbi.nlm.nih.gov/pubmed/36284330 http://dx.doi.org/10.1186/s12967-022-03662-7

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