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Modelling the epidemiological implications for SARS-CoV-2 of Christmas household bubbles in England
The emergence of SARS-CoV-2 saw severe detriments to public health being inflicted by COVID-19 disease throughout 2020. In the lead up to Christmas 2020, the UK Government sought an easement of social restrictions that would permit spending time with others over the Christmas period, whilst limiting...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598044/ https://www.ncbi.nlm.nih.gov/pubmed/36309118 http://dx.doi.org/10.1016/j.jtbi.2022.111331 |
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author | Hill, Edward M. |
author_facet | Hill, Edward M. |
author_sort | Hill, Edward M. |
collection | PubMed |
description | The emergence of SARS-CoV-2 saw severe detriments to public health being inflicted by COVID-19 disease throughout 2020. In the lead up to Christmas 2020, the UK Government sought an easement of social restrictions that would permit spending time with others over the Christmas period, whilst limiting the risk of spreading SARS-CoV-2. In November 2020, plans were published to allow individuals to socialise within ‘Christmas bubbles’ with friends and family. This policy involved a planned easing of restrictions in England between 23–27 December 2020, with Christmas bubbles allowing people from up to three households to meet throughout the holiday period. We estimated the epidemiological impact of both this and alternative bubble strategies that allowed extending contacts beyond the immediate household. We used a stochastic individual-based model for a synthetic population of 100,000 households, with demographic and SARS-CoV-2 epidemiological characteristics comparable to England as of November 2020. We evaluated five Christmas bubble scenarios for the period 23–27 December 2020, assuming our populations of households did not have symptomatic infection present and were not in isolation as the eased social restrictions began. Assessment comprised incidence and cumulative infection metrics. We tested the sensitivity of the results to a situation where it was possible for households to be in isolation at the beginning of the Christmas bubble period and also when there was lower adherence to testing, contact tracing and isolation interventions. We found that visiting family and friends over the holiday period for a shorter duration and in smaller groups was less risky than spending the entire five days together. The increases in infection from greater amounts of social mixing disproportionately impacted the eldest. We provide this account as an illustration of a real-time contribution of modelling insights to a scientific advisory group, the Scientific Pandemic Influenza Group on Modelling, Operational sub-group (SPI-M-O) for the Scientific Advisory Group for Emergencies (SAGE) in the UK, during the COVID-19 pandemic. This manuscript was submitted as part of a theme issue on “Modelling COVID-19 and Preparedness for Future Pandemics”. |
format | Online Article Text |
id | pubmed-9598044 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Author(s). Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95980442022-10-26 Modelling the epidemiological implications for SARS-CoV-2 of Christmas household bubbles in England Hill, Edward M. J Theor Biol Article The emergence of SARS-CoV-2 saw severe detriments to public health being inflicted by COVID-19 disease throughout 2020. In the lead up to Christmas 2020, the UK Government sought an easement of social restrictions that would permit spending time with others over the Christmas period, whilst limiting the risk of spreading SARS-CoV-2. In November 2020, plans were published to allow individuals to socialise within ‘Christmas bubbles’ with friends and family. This policy involved a planned easing of restrictions in England between 23–27 December 2020, with Christmas bubbles allowing people from up to three households to meet throughout the holiday period. We estimated the epidemiological impact of both this and alternative bubble strategies that allowed extending contacts beyond the immediate household. We used a stochastic individual-based model for a synthetic population of 100,000 households, with demographic and SARS-CoV-2 epidemiological characteristics comparable to England as of November 2020. We evaluated five Christmas bubble scenarios for the period 23–27 December 2020, assuming our populations of households did not have symptomatic infection present and were not in isolation as the eased social restrictions began. Assessment comprised incidence and cumulative infection metrics. We tested the sensitivity of the results to a situation where it was possible for households to be in isolation at the beginning of the Christmas bubble period and also when there was lower adherence to testing, contact tracing and isolation interventions. We found that visiting family and friends over the holiday period for a shorter duration and in smaller groups was less risky than spending the entire five days together. The increases in infection from greater amounts of social mixing disproportionately impacted the eldest. We provide this account as an illustration of a real-time contribution of modelling insights to a scientific advisory group, the Scientific Pandemic Influenza Group on Modelling, Operational sub-group (SPI-M-O) for the Scientific Advisory Group for Emergencies (SAGE) in the UK, during the COVID-19 pandemic. This manuscript was submitted as part of a theme issue on “Modelling COVID-19 and Preparedness for Future Pandemics”. The Author(s). Published by Elsevier Ltd. 2023-01-21 2022-10-26 /pmc/articles/PMC9598044/ /pubmed/36309118 http://dx.doi.org/10.1016/j.jtbi.2022.111331 Text en © 2022 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Hill, Edward M. Modelling the epidemiological implications for SARS-CoV-2 of Christmas household bubbles in England |
title | Modelling the epidemiological implications for SARS-CoV-2 of Christmas household bubbles in England |
title_full | Modelling the epidemiological implications for SARS-CoV-2 of Christmas household bubbles in England |
title_fullStr | Modelling the epidemiological implications for SARS-CoV-2 of Christmas household bubbles in England |
title_full_unstemmed | Modelling the epidemiological implications for SARS-CoV-2 of Christmas household bubbles in England |
title_short | Modelling the epidemiological implications for SARS-CoV-2 of Christmas household bubbles in England |
title_sort | modelling the epidemiological implications for sars-cov-2 of christmas household bubbles in england |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598044/ https://www.ncbi.nlm.nih.gov/pubmed/36309118 http://dx.doi.org/10.1016/j.jtbi.2022.111331 |
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