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Diagnostic and Therapeutic Challenges of Comorbid ASD, ADHD and Psychosis: A Case Report
Autism Spectrum Disorder (ASD) and attention deficit hyperactivity disorder (ADHD) comorbidity is common in clinical practice and it seems to be related to shared etiological mechanisms and genetic susceptibility. Moreover, occurrence of psychosis can further complicate these complex clinical pictur...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598192/ https://www.ncbi.nlm.nih.gov/pubmed/36285951 http://dx.doi.org/10.3390/bs12100382 |
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author | Scarselli, Veronica Martucci, Melania Novelli, Maria Galosi, Serena Romani, Maria Sogos, Carla |
author_facet | Scarselli, Veronica Martucci, Melania Novelli, Maria Galosi, Serena Romani, Maria Sogos, Carla |
author_sort | Scarselli, Veronica |
collection | PubMed |
description | Autism Spectrum Disorder (ASD) and attention deficit hyperactivity disorder (ADHD) comorbidity is common in clinical practice and it seems to be related to shared etiological mechanisms and genetic susceptibility. Moreover, occurrence of psychosis can further complicate these complex clinical pictures. Here, we discuss the case of a nine-years-old boy presenting with an episode of abnormal sustained posture of the upper limbs, resembling dystonia, at the age of 3. At this time, auditory and visual hallucinations, as well as obsessive thoughts and attentional lability were also present and a diagnosis of “Early onset psychosis” was initially made. Due to the worsening of clinical picture, several hospitalizations were necessary and pharmacological treatment with carbamazepine, risperidone and aripiprazole was carried out. Extensive clinic evaluation revealed a past medical and personal history of toe walking, weak social skills and stereotyped behavior observed and ADOS-2 Module 2 administration revealed severe Autism scores. Moreover, signs of attention and hyperactivity were consistent with ADHD diagnosis. This work highlights the importance of a complete diagnostic assessment in patients with complex presentation, suggesting the possible overlap diagnosis of ADHD and Autism even in presence of psychotic-like symptoms. |
format | Online Article Text |
id | pubmed-9598192 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95981922022-10-27 Diagnostic and Therapeutic Challenges of Comorbid ASD, ADHD and Psychosis: A Case Report Scarselli, Veronica Martucci, Melania Novelli, Maria Galosi, Serena Romani, Maria Sogos, Carla Behav Sci (Basel) Case Report Autism Spectrum Disorder (ASD) and attention deficit hyperactivity disorder (ADHD) comorbidity is common in clinical practice and it seems to be related to shared etiological mechanisms and genetic susceptibility. Moreover, occurrence of psychosis can further complicate these complex clinical pictures. Here, we discuss the case of a nine-years-old boy presenting with an episode of abnormal sustained posture of the upper limbs, resembling dystonia, at the age of 3. At this time, auditory and visual hallucinations, as well as obsessive thoughts and attentional lability were also present and a diagnosis of “Early onset psychosis” was initially made. Due to the worsening of clinical picture, several hospitalizations were necessary and pharmacological treatment with carbamazepine, risperidone and aripiprazole was carried out. Extensive clinic evaluation revealed a past medical and personal history of toe walking, weak social skills and stereotyped behavior observed and ADOS-2 Module 2 administration revealed severe Autism scores. Moreover, signs of attention and hyperactivity were consistent with ADHD diagnosis. This work highlights the importance of a complete diagnostic assessment in patients with complex presentation, suggesting the possible overlap diagnosis of ADHD and Autism even in presence of psychotic-like symptoms. MDPI 2022-10-06 /pmc/articles/PMC9598192/ /pubmed/36285951 http://dx.doi.org/10.3390/bs12100382 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Scarselli, Veronica Martucci, Melania Novelli, Maria Galosi, Serena Romani, Maria Sogos, Carla Diagnostic and Therapeutic Challenges of Comorbid ASD, ADHD and Psychosis: A Case Report |
title | Diagnostic and Therapeutic Challenges of Comorbid ASD, ADHD and Psychosis: A Case Report |
title_full | Diagnostic and Therapeutic Challenges of Comorbid ASD, ADHD and Psychosis: A Case Report |
title_fullStr | Diagnostic and Therapeutic Challenges of Comorbid ASD, ADHD and Psychosis: A Case Report |
title_full_unstemmed | Diagnostic and Therapeutic Challenges of Comorbid ASD, ADHD and Psychosis: A Case Report |
title_short | Diagnostic and Therapeutic Challenges of Comorbid ASD, ADHD and Psychosis: A Case Report |
title_sort | diagnostic and therapeutic challenges of comorbid asd, adhd and psychosis: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598192/ https://www.ncbi.nlm.nih.gov/pubmed/36285951 http://dx.doi.org/10.3390/bs12100382 |
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