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Kinesin Eg5 Selective Inhibition by Newly Synthesized Molecules as an Alternative Approach to Counteract Breast Cancer Progression: An In Vitro Study

SIMPLE SUMMARY: Breast cancer is the most widespread and diagnosed cancer in women. This study tested newly synthesized Eg5 inhibitors to find valid therapeutic alternatives to common drugs able to counteract breast cancer progression. Our results evidence that thiadiazole-based Eg5 inhibitors, 2 an...

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Detalles Bibliográficos
Autores principales: Ricci, Alessia, Cataldi, Amelia, Carradori, Simone, Zara, Susi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598199/
https://www.ncbi.nlm.nih.gov/pubmed/36290354
http://dx.doi.org/10.3390/biology11101450

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