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Evaluating the Haemodynamic Performance of Endografts for Complex Aortic Arch Repair
Thoracic endovascular aortic repair (TEVAR) of aortic aneurysms and dissections involving the arch has evolved over the last two decades. Compared to conventional surgical methods, endovascular repair offers a less invasive treatment option with lower risk and faster recovery. Endografts used in TEV...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598215/ https://www.ncbi.nlm.nih.gov/pubmed/36290541 http://dx.doi.org/10.3390/bioengineering9100573 |
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author | Sengupta, Sampad Zhu, Yu Hamady, Mohamad Xu, Xiao Yun |
author_facet | Sengupta, Sampad Zhu, Yu Hamady, Mohamad Xu, Xiao Yun |
author_sort | Sengupta, Sampad |
collection | PubMed |
description | Thoracic endovascular aortic repair (TEVAR) of aortic aneurysms and dissections involving the arch has evolved over the last two decades. Compared to conventional surgical methods, endovascular repair offers a less invasive treatment option with lower risk and faster recovery. Endografts used in TEVAR vary in design depending on the procedure and application. Novel endografts (e.g., branched stent-graft) were developed to ensure perfusion of blood to the supra-aortic vessels, but their haemodynamic performance and long-term durability have not been adequately studied. This review focuses on the use of computational modelling to study haemodynamics in commercially available endografts designed for complex aortic arch repair. First, we summarise the currently adopted workflow for computational fluid dynamics (CFD) modelling, including geometry reconstruction, boundary conditions, flow models, and haemodynamic metrics of interest. This is followed by a review of recently (2010-present) published CFD studies on complex aortic arch repair, using both idealized and patient-specific models. Finally, we introduce some of the promising techniques that can be potentially applied to predict post-operative outcomes. |
format | Online Article Text |
id | pubmed-9598215 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95982152022-10-27 Evaluating the Haemodynamic Performance of Endografts for Complex Aortic Arch Repair Sengupta, Sampad Zhu, Yu Hamady, Mohamad Xu, Xiao Yun Bioengineering (Basel) Review Thoracic endovascular aortic repair (TEVAR) of aortic aneurysms and dissections involving the arch has evolved over the last two decades. Compared to conventional surgical methods, endovascular repair offers a less invasive treatment option with lower risk and faster recovery. Endografts used in TEVAR vary in design depending on the procedure and application. Novel endografts (e.g., branched stent-graft) were developed to ensure perfusion of blood to the supra-aortic vessels, but their haemodynamic performance and long-term durability have not been adequately studied. This review focuses on the use of computational modelling to study haemodynamics in commercially available endografts designed for complex aortic arch repair. First, we summarise the currently adopted workflow for computational fluid dynamics (CFD) modelling, including geometry reconstruction, boundary conditions, flow models, and haemodynamic metrics of interest. This is followed by a review of recently (2010-present) published CFD studies on complex aortic arch repair, using both idealized and patient-specific models. Finally, we introduce some of the promising techniques that can be potentially applied to predict post-operative outcomes. MDPI 2022-10-18 /pmc/articles/PMC9598215/ /pubmed/36290541 http://dx.doi.org/10.3390/bioengineering9100573 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sengupta, Sampad Zhu, Yu Hamady, Mohamad Xu, Xiao Yun Evaluating the Haemodynamic Performance of Endografts for Complex Aortic Arch Repair |
title | Evaluating the Haemodynamic Performance of Endografts for Complex Aortic Arch Repair |
title_full | Evaluating the Haemodynamic Performance of Endografts for Complex Aortic Arch Repair |
title_fullStr | Evaluating the Haemodynamic Performance of Endografts for Complex Aortic Arch Repair |
title_full_unstemmed | Evaluating the Haemodynamic Performance of Endografts for Complex Aortic Arch Repair |
title_short | Evaluating the Haemodynamic Performance of Endografts for Complex Aortic Arch Repair |
title_sort | evaluating the haemodynamic performance of endografts for complex aortic arch repair |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598215/ https://www.ncbi.nlm.nih.gov/pubmed/36290541 http://dx.doi.org/10.3390/bioengineering9100573 |
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