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Designing an optimization model for the vaccine supply chain during the COVID-19 pandemic
The COVID-19 pandemic has affected people's lives worldwide. Among various strategies being applied to addressing such a global crisis, public vaccination has been arguably the most appropriate approach to control a pandemic. However, vaccine supply chain and management have become a new challe...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598262/ https://www.ncbi.nlm.nih.gov/pubmed/36312907 http://dx.doi.org/10.1016/j.eswa.2022.119009 |
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author | Valizadeh, Jaber Boloukifar, Shadi Soltani, Sepehr Jabalbarezi Hookerd, Ehsan Fouladi, Farzaneh Andreevna Rushchtc, Anastasia Du, Bo Shen, Jun |
author_facet | Valizadeh, Jaber Boloukifar, Shadi Soltani, Sepehr Jabalbarezi Hookerd, Ehsan Fouladi, Farzaneh Andreevna Rushchtc, Anastasia Du, Bo Shen, Jun |
author_sort | Valizadeh, Jaber |
collection | PubMed |
description | The COVID-19 pandemic has affected people's lives worldwide. Among various strategies being applied to addressing such a global crisis, public vaccination has been arguably the most appropriate approach to control a pandemic. However, vaccine supply chain and management have become a new challenge for governments. In this study, a solution for the vaccine supply chain is presented to address the hurdles in the public vaccination program according to the concerns of the government and the organizations involved. For this purpose, a robust bi-level optimization model is proposed. At the upper level, the risk of mortality due to the untimely supply of the vaccine and the risk of inequality in the distribution of the vaccine is considered. All costs related to the vaccine supply chain are considered at the lower level, including the vaccine supply, allocation of candidate centers for vaccine injection, cost of maintenance and injection, transportation cost, and penalty cost due to the vaccine shortage. In addition, the uncertainty of demand for vaccines is considered with multiple scenarios of different demand levels. Numerical experiments are conducted based on the vaccine supply chain in Kermanshah, Iran, and the results show that the proposed model significantly reduces the risk of mortality and inequality in the distribution of vaccines as well as the total cost, which leads to managerial insights for better coordination of the vaccination network during the COVID-19 pandemic. |
format | Online Article Text |
id | pubmed-9598262 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95982622022-10-26 Designing an optimization model for the vaccine supply chain during the COVID-19 pandemic Valizadeh, Jaber Boloukifar, Shadi Soltani, Sepehr Jabalbarezi Hookerd, Ehsan Fouladi, Farzaneh Andreevna Rushchtc, Anastasia Du, Bo Shen, Jun Expert Syst Appl Article The COVID-19 pandemic has affected people's lives worldwide. Among various strategies being applied to addressing such a global crisis, public vaccination has been arguably the most appropriate approach to control a pandemic. However, vaccine supply chain and management have become a new challenge for governments. In this study, a solution for the vaccine supply chain is presented to address the hurdles in the public vaccination program according to the concerns of the government and the organizations involved. For this purpose, a robust bi-level optimization model is proposed. At the upper level, the risk of mortality due to the untimely supply of the vaccine and the risk of inequality in the distribution of the vaccine is considered. All costs related to the vaccine supply chain are considered at the lower level, including the vaccine supply, allocation of candidate centers for vaccine injection, cost of maintenance and injection, transportation cost, and penalty cost due to the vaccine shortage. In addition, the uncertainty of demand for vaccines is considered with multiple scenarios of different demand levels. Numerical experiments are conducted based on the vaccine supply chain in Kermanshah, Iran, and the results show that the proposed model significantly reduces the risk of mortality and inequality in the distribution of vaccines as well as the total cost, which leads to managerial insights for better coordination of the vaccination network during the COVID-19 pandemic. Elsevier Ltd. 2023-03-15 2022-10-26 /pmc/articles/PMC9598262/ /pubmed/36312907 http://dx.doi.org/10.1016/j.eswa.2022.119009 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Valizadeh, Jaber Boloukifar, Shadi Soltani, Sepehr Jabalbarezi Hookerd, Ehsan Fouladi, Farzaneh Andreevna Rushchtc, Anastasia Du, Bo Shen, Jun Designing an optimization model for the vaccine supply chain during the COVID-19 pandemic |
title | Designing an optimization model for the vaccine supply chain during the COVID-19 pandemic |
title_full | Designing an optimization model for the vaccine supply chain during the COVID-19 pandemic |
title_fullStr | Designing an optimization model for the vaccine supply chain during the COVID-19 pandemic |
title_full_unstemmed | Designing an optimization model for the vaccine supply chain during the COVID-19 pandemic |
title_short | Designing an optimization model for the vaccine supply chain during the COVID-19 pandemic |
title_sort | designing an optimization model for the vaccine supply chain during the covid-19 pandemic |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598262/ https://www.ncbi.nlm.nih.gov/pubmed/36312907 http://dx.doi.org/10.1016/j.eswa.2022.119009 |
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