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Identification of a Small Molecule That Inhibits the Interaction of LPS Transporters LptA and LptC

The need for novel antibiotics has become imperative with the increasing prevalence of antibiotic resistance in Gram-negative bacteria in clinics. Acting as a permeability barrier, lipopolysaccharide (LPS) protects Gram-negative bacteria against drugs. LPS is synthesized in cells and transported to...

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Detalles Bibliográficos
Autores principales:	Dai, Xiaowei, Yuan, Min, Lu, Yu, Zhu, Xiaohong, Liu, Chao, Zheng, Yifan, Si, Shuyi, Yuan, Lijie, Zhang, Jing, Li, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598311/ https://www.ncbi.nlm.nih.gov/pubmed/36290043 http://dx.doi.org/10.3390/antibiotics11101385

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