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Perhexiline Therapy in Patients with Type 2 Diabetes: Incremental Insulin Resistance despite Potentiation of Nitric Oxide Signaling

Perhexiline (Px) inhibits carnitine palmitoyltransferase 1 (CPT1), which controls uptake of long chain fatty acids into mitochondria. However, occasional cases of hypoglycaemia have been reported in Px-treated patients, raising the possibility that Px may also increase sensitivity to insulin. Furthe...

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Detalles Bibliográficos
Autores principales:	Chong, Cher-Rin, Liu, Saifei, Imam, Hasan, Heresztyn, Tamila, Sallustio, Benedetta C., Chirkov, Yuliy Y., Horowitz, John D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598312/ https://www.ncbi.nlm.nih.gov/pubmed/36289640 http://dx.doi.org/10.3390/biomedicines10102381

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