Postnatal Conditional Deletion of Bcl11b in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington’s Disease

The dysregulation of striatal gene expression and function is linked to multiple diseases, including Huntington’s disease (HD), Parkinson’s disease, X-linked dystonia-parkinsonism (XDP), addiction, autism, and schizophrenia. Striatal medium spiny neurons (MSNs) make up 90% of the neurons in the stri...

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Detalles Bibliográficos
Autores principales: Song, Sicheng, Creus Muncunill, Jordi, Galicia Aguirre, Carlos, Tshilenge, Kizito-Tshitoko, Hamilton, B. Wade, Gerencser, Akos A., Benlhabib, Houda, Cirnaru, Maria-Daniela, Leid, Mark, Mooney, Sean D., Ellerby, Lisa M., Ehrlich, Michelle E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598565/
https://www.ncbi.nlm.nih.gov/pubmed/36289639
http://dx.doi.org/10.3390/biomedicines10102377

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