Aerosol Inhalation Delivery of Ceftriaxone in Mice: Generation Procedure, Pharmacokinetics, and Therapeutic Outcome

Aerosol inhalation delivery of ceftriaxone in mice was investigated. An ultrasonic nebulizer within the ranges of mean particle diameter 0.5–1.5 μm and mass concentration 0.01–0.6 μg/cm(3) was used in inhalation experiments. Pharmacokinetic measurements were carried out using a nose-only chamber. Ce...

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Detalles Bibliográficos
Autores principales: Valiulin, Sergey V., Onischuk, Andrei A., Baklanov, Anatoly M., An’kov, Sergey V., Dubtsov, Sergey N., Alekseev, Alexander A., Shkil, Nikolay N., Nefedova, Ekaterina V., Plokhotnichenko, Maria E., Tolstikova, Tatyana G., Dolgov, Arseniy M., Dultseva, Galina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598611/
https://www.ncbi.nlm.nih.gov/pubmed/36289963
http://dx.doi.org/10.3390/antibiotics11101305

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